CRISPR/CAS9 en guideRNA zijn de middelen om DNA aan te passen.
Using synthetic COVID-19 virus RNA fragments, we have been able to consistently detect COVID-19 target sequences in a range between 20 and 200 aM (10-100 copies per microliter of input). The test can be carried out starting with RNA purified from patient samples, as is used for qRT-PCR assays, and can be read out using a dipstick in less than an hour, without requiring elaborate instrumentation.
https://www.broadinstitute.org/files/publications/special/COVID-19%20detection%20(updated).pdf